Unilateral generalized morphea: A case report
نویسنده
چکیده مقاله:
Morphea is a localized form of scleroderma characterized by sclerotic plaques limited to the skin. Although its cause is unknown, genetic, infectious and autoimmune mechanisms have been suggessed in the pathogenesis of the morphea. It is more common among childen and young women. Although the prognosis is generally good, it sometimes causes significant morbidity. Morphea has five subtypes as plaque, generalized, bullosa, deep and linear. Unilateral forms of generalized morphea have rarely been reported in the literature. Our case has been presented because it is very rarely seen.
منابع مشابه
Unilateral generalized morphea: A case report and literature review
Morphea is an autoimmune connective tissue disease of the dermis and subcutaneous fat characterized by sclerosis due to excessive collagen deposition. Morphea is classified into different subtypes based on clinical and histological characteristics of cutaneous lesions. An extremely rare subtype of morphea is termed unilateral generalized morphea (UGM). UGM is characterized by indurated plaques ...
متن کاملGeneralized morphea: a case report.
Generalized morphea is a subtype of localized scleroderma that lacks systemic manifestations. It is a rare condition in which idiopathic sclerosis of the skin occurs in a widespread manner. We report a 37-year old Thai female who presented with multiple hypopigmented lesions on right leg and right arm with a skin biopsy showing the typical sclerotic change. The patient responded to treatment wi...
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Generalized morphea is a subtype of localized scleroderma, which lacks systemic manifestations and displays widespread, multiple, well-circumscribed, indurated plaques. We represent a 46-year-old woman with generalized morphea. More than 3 years ago she developed multiple, nonpruritic plaques symmetrically on the trunk and extremities. The patient’s clinical history, laboratory analysis and his...
متن کامل[Unilateral generalized morphea: a case and literature review].
Localized scleroderma is a connective tissue disorder generally involving de entire dermis and usually limited to the subcutaneous tissue; however, it may progress to large indurated plaques, growth retardation, muscle atrophy, and even to flexion deformities or poorly healing ulcers. Unilateral generalized morphea is an extremely rare variant of localized scleroderma which has seldom been repo...
متن کاملMorphea-A Case Report
Introduction: Skin can be the site of manifestations of many systemic diseases. Morphea which is also includes thickening & hardening of skin & sub cutaneous tissues may have a varying range of manifestations. Surgery is rarely indicated. Case Report: A 30 year old female came with complaints of dark brown sclerotic plaque over the upper half of the right thigh with restriction of movements at ...
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Morphea is a localized form of scleroderma in which there is predominant skin involvement, with occasional involvement of subjacent muscles and usually spares the internal organs. Thyroid dysfunction has been reported in systemic sclerosis but it has been rarely reported in morphea. There are few case reports of plaque-type morphea associated with autoimmune thyroiditis but generalized morphea ...
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عنوان ژورنال
دوره 14 شماره 2
صفحات 73- 75
تاریخ انتشار 2011-07-01
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